Here are the slides for my talk at the “Howard University Math-Bio Virtual Workshop on Mitigation of Future Pandemics” last Saturday. One surprising thing (to me) the model predicted, shown on slide 40, is that the median fraction of those previously infected or vaccinated (or both) was 40% or higher during the omicron wave. I was pleased and relieved to then find that recent CDC serology results validate this prediction.
I gave a talk at the International Conference on Complex Acute Illness (ICCAI) with the title Forecasting COVID-19. I talked about some recent work with FDA collaborators on scoring a large number of publicly available epidemic COVID-19 projection models and show that they are unable to reliably forecast COVID-19 beyond a few weeks. The slides are here.
Slides for Covid-19 talk
Here are my slides for my recent COVID-19 talk at the Centre for Applied Mathematics in BioScience and Medicine (CAMBAM). It’s an updated version of the one I gave to the FDA.
Here are the slides for my webinar at FDA today .
Here are my slides for the talk I gave today at The 4th workshop on Advanced Methods in Theoretical Neuroscience, Structure and disorder: From random connections to functional circuits, July 10-12 2019, Göttingen, Germany.
Here are the slides for the talk that Shashaank Vattikuti gave at the “From Neural Activity to Behavior: Computational Modeling of the Nervous System” Symposium held at NIH, April 18-19, 2019. The talk is on our work to quantify mental illness.
Audio of SIAM talk
Here is an audio recording synchronized to slides of my talk a week and a half ago in Pittsburgh. I noticed some places where I said the wrong thing such as conflating neuron with synapse. I also did not explain the learning part very well. I should point out that we are not applying a control to the network. We train a set of weights so that given some initial condition, the neuron firing rates follow a specified target pattern. I also made a joke that implied that the Recursive Least Squares algorithm dates to 1972. That is not correct. It goes back much further back than that. I also take a pot shot at physicists. It was meant as a joke of course and describes many of my own papers.
Talk at SIAM Annual Meeting 2017
I gave an invited plenary talk at the 2017 Society of Applied and Industrial Mathematics Annual Meeting in Pittsburgh yesterday. My slides are here. I talked about some very new work on chaos and learning in spiking neural networks. My fellow Chris Kim and I were producing graphs up to a half hour before my talk! I’m quite excited about this work and I hope to get it published soon.
During my talk, I made an offhand threat that my current Mac would be the last one I buy. I made the joke because it was the first time that I could not connect to a projector with my laptop since I started using Mac almost 20 years ago. I switched to Mac from Linux back then because it was a Unix environment where I didn’t need to be a systems administrator to print and project. However, Linux has made major headway in the past two decades while Mac is backsliding. So, I’m seriously thinking of following through. I’ve been slowly getting disenchanted with Apple products over the past three years but I am especially disappointed with my new MacBook Pro. I have the one with the silly touch screen bar. The first thing the peeves me is that the activate Siri key is right next to the delete key so I accidentally hit and then have to reject Siri every five minutes. What mostly ties me to Mac right now is the Keynote presentation software, which I like(d) because it is easy to embed formulas and PDF files into. It is much harder to do the same in PowerPoint and I haven’t found an open source version that is as easy to use. However, Keynote keeps hanging on my new machine. I also get this situation where my embedded equations will randomly disappear and then reappear. Luckily I did a quick run through just before my talk and noticed that the vanished equations reappeared and I could delete them. Thus, the Keynote appeal has definitely diminished. Now, if someone would like to start an open source Keynote project with me… Finally, the new Mac does not seem any faster than my old Mac (it still takes forever to boot up) and Bard Ermentrout told me that his dynamical systems software tool XPP runs five times slower. So, any suggestions for a new machine?
Talk at Maryland
I gave a talk at the Center for Scientific Computing and Mathematical Modeling at the University of Maryland today. My slides are here. I apologize for the excessive number of pages but I had to render each build in my slides, otherwise many would be unreadable. A summary of the work and links to other talks and papers can be found here.
Talk at Imperial College
I’m currently visiting the MRC Clinical Sciences Centre of Imperial College, London to give a talk on my obesity work. The slides are here.
Talk in Göttingen
I’m currently in Göttingen, Germany at the Bernstein Sparks Workshop: Beyond mean field theory in the neurosciences, a topic near and dear to my heart. The slides for my talk are here. Of course no trip to Göttingen would be complete without a visit to Gauss’s grave and Max Born’s house. Photos below.
Talk at Michigan
Talk at UMBC
I’m giving a talk at University of Maryland, Baltimore County today at noon. The talk will be similar to the one I gave at SMB this past summer. Slides can be found here.
I just gave an invited plenary talk at the joint annual meeting of the Japanese Society of Mathematical Biology and Society of Mathematical Biology in Osaka Japan. I talked about my work on steroid-regulated gene transcription. The slides are here. Previous posts on the topic, including background summaries, can be found here.
Talk at Jackfest
I’m currently in Banff, Alberta for a Festschrift for Jack Cowan (webpage here). Jack is one of the founders of theoretical neuroscience and has infused many important ideas into the field. The Wilson-Cowan equations that he and Hugh Wilson developed in the early seventies form a foundation for both modeling neural systems and machine learning. My talk will summarize my work on deriving “generalized Wilson-Cowan equations” that include both neural activity and correlations. The slides can be found here. References and a summary of the work can be found here. All videos of the talks can be found here.
Addendum: 17:44. Some typos in the talk were fixed.
Addendum: 18:25. I just realized I said something silly in my talk. The Legendre transform is an involution because the transform of the transform is the inverse. I said something completely inane instead.
Slides for talk on gene expression
Talk in Taiwan
I’m currently at the National Center for Theoretical Sciences, Math Division, on the campus of the National Tsing Hua University, Hsinchu for the 2013 Conference on Mathematical Physiology. The NCTS is perhaps the best run institution I’ve ever visited. They have made my stay extremely comfortable and convenient.
Here are the slides for my talk on Correlations, Fluctuations, and Finite Size Effects in Neural Networks. Here is a list of references that go with the talk
E. Hildebrand, M.A. Buice, and C.C. Chow, `Kinetic theory of coupled oscillators,’ Physical Review Letters 98 , 054101 (2007) [PRL Online] [PDF]
M.A. Buice and C.C. Chow, `Correlations, fluctuations and stability of a finite-size network of coupled oscillators’. Phys. Rev. E 76 031118 (2007) [PDF]
M.A. Buice, J.D. Cowan, and C.C. Chow, ‘Systematic Fluctuation Expansion for Neural Network Activity Equations’, Neural Comp., 22:377-426 (2010) [PDF]
C.C. Chow and M.A. Buice, ‘Path integral methods for stochastic differential equations’, arXiv:1009.5966 (2010).
M.A. Buice and C.C. Chow, `Effective stochastic behavior in dynamical systems with incomplete incomplete information.’ Phys. Rev. E 84:051120 (2011).
MA Buice and CC Chow. Dynamic finite size effects in spiking neural networks. PLoS Comp Bio 9:e1002872 (2013).
MA Buice and CC Chow. Generalized activity equations for spiking neural networks. Front. Comput. Neurosci. 7:162. doi: 10.3389/fncom.2013.00162, arXiv:1310.6934.
Here is the link to relevant posts on the topic.
Talk at GRC
I’m currently in Mt. Snow, Vermont to give a talk at the Gordon Research Conference on Computer Aided Drug Design. Yes, I know nothing about drug design. I am here because the organizer, Anthony Nicholls, asked me to give a pedagogical talk on Bayesian Inference. My slides are here. I only arrived yesterday but the few talks I’ve seen have been quite interesting. One interesting aspect of this conference is that many of the participants are from industry. The evening sessions are meant to be of more general interest. Last night were two talks about how to make science more reproducible. As I’ve posted before, many published results are simply wrong. The very enterprising Elizabeth Iorns has started something called the Reproducibility Initiative. I am not completely clear about how it works but it is part of another entity she started called Science Exchange, which helps to facilitate collaborations with a fee-for-service model. The Reproducibility Initiative piggy backs on Science Exchange by providing a service (for a fee) to validate any particular result. Papers that pass approval get a stamp of approval. It is expected that pharma would be interested in using this service so they can inexpensively check if possible drug targets actually hold up. Many drugs fail at phase three of clinical trials because they’ve been shown to be ineffective and this may be due to the target being wrong to start with.
On a final note, I flew to Albany and drove here. Unlike in the past when I would have printed out a map, I simply assumed that I could use Google Maps on my smart phone to get here. However, Google Maps doesn’t really know where Mt. Snow is. It tried to take me up a dirt road to the back of the ski resort. Also, just after I turned up the road, the phone signal disappeared so I was blind and had no paper backup. I was suspicious that this was the right way to go so I turned back to the main highway in hopes of finding a signal or a gas station to ask for directions. A few miles down Route 9, I finally did get a signal and also found a sign that led me the way. Google Maps still tried to take me the wrong way. I should have followed what I always tell my daughter – Always have a backup plan.
Slides for Hopkins talk
I gave the Bodian Seminar at the Zanvyl Krieger Mind/Brain Institute of Johns Hopkins today. I talked about cortical dynamics in the presence of conflicting stimuli. My slides are here. A summary of part of my talk can be found here. Other pertinent papers can be found here and here.
Slides for ACP talk
I just gave a talk on obesity at a diabetes course at the American College of Physicians meeting in San Francisco. My slides are here.